Soft tissue tumors: Extraskeletal myxoid chondrosarcoma

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Soft tissue tumors: Extraskeletal myxoid chondrosarcoma

Macroscopic findings: the tumour presents as lobulated or multinodular mass, generally well circumscribed by a distinct fibrous capsule.The size of the tumour at the time of diagnosis may vary from 1 to about 20 cm (mean size: about 7 cm). Histology: typically, tumour nodules are composed of round or slightly elongated cells, with minimal features of chondroblasts, separated by mucoid substance...

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Extraskeletal myxoid chondrosarcoma arising from the clavicle.

This report presents an extremely rare case of extraskeletal myxoid chondrosarcoma (EMC) arising from the clavicular periosteum. To the best of our knowledge, this may be the first detailed report of its clinicopathological findings. The patient was a 48-year-old man. Plain radiography and CT did not demonstrate any osteolytic lesion or periosteal reaction in the right clavicle. However, MRI sh...

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Heart metastasis of extraskeletal myxoid chondrosarcoma.

Isolated, remote heart metastasis of myxoid chondrosarcoma is extremely rare. We present an unusual case of isolated remote metastasis of extraosseus myxoid chondrosarcoma from the right ankle region to the right ventricle, its clinical course, and treatment in a 46-year-old woman. Although heart biopsy done before the surgery revealed myxoma, histopathologic diagnosis of the heart tumor was co...

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Primary extraskeletal myxoid chondrosarcoma in cerebellum

Rationale: Extraskeletal myxoid chondrosarcoma (EMC) is a rare malignant neoplasm of which intracranial EMC is the rarest. Patientconcerns:We present an unusual case report of a 41-year-old woman who was sent to the emergency department for a sudden headache and other symptoms related to increased intracranial pressure. Interventions: Emergent CT revealed an occupying lesion in the left cerebel...

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Next generation sequencing of extraskeletal myxoid chondrosarcoma

Extraskeletal myxoid chondrosarcoma (EMC) is an indolent translocation-associated soft tissue sarcoma with a high propensity for metastases. Using a clinical sequencing approach, we genomically profiled patients with metastatic EMC to elucidate the molecular biology and identify potentially actionable mutations. We also evaluated potential predictive factors of benefit to sunitinib, a multi-tar...

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2011

ISSN: 1768-3262

DOI: 10.4267/2042/38141